Actually, I think there is a " Je ne sai quoi" in every genre and all forms of art, be it images on canvas, real paintings, music, sculptures, movies, jewelry, just everything art.
Yes, even digital and AI art are inspirational.
Sometimes, one can't say why they were moved, inspired and taken over by a work, but it happens.
Not every work, however, is going to make this grade. Not every artist is going to knock the ball out of the park with their ideas and concepts. Sometimes a person is able to connect with people via their art, but it's not always within an artist's life that their work is captivating to others.
"I don't know what" it is about that work that I love so much! I've had that feeling about music and art all my life.